Darbepoetin-α prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure
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منابع مشابه
Darbepoetin- prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure
Rastogi S, Imai M, Sharov VG, Mishra S, Sabbah HN. Darbepoetinprevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure. Am J Physiol Heart Circ Physiol 295: H2475–H2482, 2008. First published October 24, 2008; doi:10.1152/ajpheart.00074.2008.—In anemic patients with heart failure (HF), erythropoietin-type drugs can elicit clinical improvement. This s...
متن کاملDarbepoetin-alpha prevents progressive left ventricular dysfunction and remodeling in nonanemic dogs with heart failure.
In anemic patients with heart failure (HF), erythropoietin-type drugs can elicit clinical improvement. This study examined the effects of chronic monotherapy with darbepoetin-alpha (DARB) on left ventricular (LV) function and remodeling in nonanemic dogs with advanced HF. HF [LV ejection fraction (EF) approximately 25%] was produced in 14 dogs by intracoronary microembolizations. Dogs were rand...
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OBJECTIVES This study examined the effects of long-term monotherapy with rosuvastatin (RSV) on the progression of left ventricular (LV) dysfunction and remodeling in dogs with heart failure (HF). BACKGROUND 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors or "statins" possess other noncholesterol-lowering properties that include inhibiting proinflammatory cytokines, attenuating LV h...
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ژورنال
عنوان ژورنال: American Journal of Physiology-Heart and Circulatory Physiology
سال: 2008
ISSN: 0363-6135,1522-1539
DOI: 10.1152/ajpheart.00074.2008